Clinical trial · Interventional
CO2 Absorption During Laparoscopy
Evaluation of Adding 4% of Oxygen and 10% of Nitrous Oxide to the CO2 Pneumoperitoneum Upon CO2 Resorption.
NCT01340989CI-TRIAL-00005690completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
CO2 absorption from the pneumoperitoneum increases over time during laparoscopic procedures. Adding 4% of oxygen to the carbon dioxide was shown in rabbits to decrease CO2 resorbtion through prevention of mesothelial hypoxia. We want to prove this concept in human and expand it to the use of full conditioning.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pneumoperitoneum | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| alteration of the insufflation gas | Procedure | — | UNRESOLVED |
| full conditioning | Procedure | — | UNRESOLVED |
| standard pneumoperitoneum | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- 4% oxygen
- description
- addition of 4% oxygen to the CO2 pneumoperitoneum
- interventionNames
- Procedure: alteration of the insufflation gas
- type
- EXPERIMENTAL
- label
- full conditioning
- description
- full conditioning of the peritoneal cavity by the laparoscopic gas: 4% oxygen, 10% nitrous oxide, humidification and set temperature of 32°C
- interventionNames
- Procedure: full conditioning
- type
- ACTIVE_COMPARATOR
- label
- CO2 pneumoperitoneum
- description
- standard laparoscopy with CO2 pneumoperitoneum
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * Women/men planned to undergo a laparoscopic intervention for at least 1 hour and having signed the informed consent Exclusion Criteria: * Pregnancy * Immunodeficiency * Refuse or unable to sign informed consent * Chronic disease (i.e. COPD, Crohn, cardiac…)
References
Publications (0)
Data not yet available
No reference posted for this study.