Clinical trial · Interventional
Rapid Easy Strength Training (REST) to Improve Function in Late Stage Cancer
Phase II Randomized Controlled Trial of Rapid and Easy Strength Training to Preserve Function in Late Stage Cancer
NCT01334983CI-TRIAL-00071463RESTcompletedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether a gentle physical conditioning program comprised of isotonic resistive strengthening and pedometer-directed walking can improve the physical functioning and fatigue of patients with late stage lung or colon cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| REST | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- REST
- description
- Participants instructed in individualized Rapid Easy Strength Training and pedometer-based walking programs
- interventionNames
- Behavioral: REST
- type
- NO_INTERVENTION
- label
- Wait list control
- description
- Participants instructed in REST after completing week 8 outcome measures
Primary outcomes (1)
- measure
- Ambulatory Post Acute Care Basic Mobility Short Form
- timeFrame
- 8 weeks
- description
- Patient reported outcome with 18 items assessed functionality in basic mobility. Response option for all items is a 4 level Likert scale
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of Stage III or IV NSCLC or extensive stage SCLC, or Stage IV colon cancer * fluency in the English language * Intact cognitive status (Folstein mini-mental score \> 25). Exclusion Criteria: * Pain numeric rating scale (NRS) scores \> 7/10, * Fatigue NRS score \> 8/10, * paralysis of \> 2 limbs (\< antigravity strength in all major muscle groups), * Severe cerebellar ataxia, * Chronic (\> 1 year) non-cancer pain either \>5/10 or causing the patient to apply for or receive disability payments. * Severe medical or psychiatric co-morbidities such as major depression or unstable angina
References
Publications (0)
Data not yet available
No reference posted for this study.