Clinical trial · Interventional
Resistance Training and Physical Functioning in Head and Neck Cancer Patients
NCT01332682CI-TRIAL-00070569completedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this feasibility study is to examine the safety and effect of resistance training on muscle strength, lean body mass, physical functioning, fatigue, and quality of life in head and neck cancer patients receiving radiation therapy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Laryngeal Cancer | Malignant Laryngeal Neoplasm | CURATED_EXACT | 0.92 |
| Pharyngeal Cancer | Malignant Pharyngeal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nutrition Counseling | Behavioral | — | UNRESOLVED |
| Resistance Training and Nutrition Counseling | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Resistance Training and Nutrition Counseling
- interventionNames
- Behavioral: Resistance Training and Nutrition Counseling
- type
- OTHER
- label
- Nutrition Counseling
- interventionNames
- Behavioral: Nutrition Counseling
Primary outcomes (1)
- measure
- safety of head and neck cancer patients
- timeFrame
- daily (up to 12 weeks)
- description
- adverse events
Secondary outcomes (7)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion criteria: * cancer of the oral cavity, pharynx, larynx, nasal cavity/sinuses, or salivary gland * ≥ 18 years of age * English speaking * radiation therapy planned or underway \< 1 week, and * able to stand Exclusion Criteria: * dementia or organic brain syndrome * severe emotional distress * active schizophrenia * quadriplegia or loss of use of limbs or torso * tendon rupture * muscle tear * cancer recurrence * another diagnoses of cancer in the past 5 years, and * oncologist refuses to allow screening for possible study participation
References
Publications (3)
- BACKGROUNDRogers LQ, Rao K, Malone J, Kandula P, Ronen O, Markwell SJ, Courneya KS, Robbins KT. Factors associated with quality of life in outpatients with head and neck cancer 6 months after diagnosis. Head Neck. 2009 Sep;31(9):1207-14. doi: 10.1002/hed.21084. PMID 19360748
- BACKGROUNDRogers LQ, Malone J, Rao K, Courneya KS, Fogleman A, Tippey A, Markwell SJ, Robbins KT. Exercise preferences among patients with head and neck cancer: prevalence and associations with quality of life, symptom severity, depression, and rural residence. Head Neck. 2009 Aug;31(8):994-1005. doi: 10.1002/hed.21053. PMID 19340875
- RESULTRogers LQ, Anton PM, Fogleman A, Hopkins-Price P, Verhulst S, Rao K, Malone J, Robbs R, Courneya KS, Nanavati P, Mansfield S, Robbins KT. Pilot, randomized trial of resistance exercise during radiation therapy for head and neck cancer. Head Neck. 2013 Aug;35(8):1178-88. doi: 10.1002/hed.23118. Epub 2012 Jul 30. PMID 22847995