Clinical trial · Interventional
The Effects of Epidural Anesthesia on the Bioavailability of Nitric Oxide and Renal Function in Patients Undergoing Laparoscopic Surgery
NCT01325844CI-TRIAL-00006203completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study was designed to investigate the effects of epidural anesthesia combined with general anesthesia during laparoscopic surgery. The investigators hypothesized that epidural anesthesia will effectively block the activation of the sympathetic nervous system during surgery, thus activating nitric oxide and reducing splanchnic ischemia and decrease in postoperative renal function.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Epidural anesthesia | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- G group
- description
- G group = General anesthesia group
- type
- EXPERIMENTAL
- label
- G+E group
- description
- G+E group = General anesthesia + epidural anesthesia group
- interventionNames
- Procedure: Epidural anesthesia
Primary outcomes (1)
- measure
- blood pressure with heart rate variability
- timeFrame
- 10 minutes after anesthesia induction
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * ASA class 1 or 2 adult patients scheduled for endoscopic prostatectomy Exclusion Criteria: * Patient refusal * Patients on diuretics * Patients with renal failure (eGFR \< 60 ml/min/1.73 m2)
References
Publications (0)
Data not yet available
No reference posted for this study.