Clinical trial · Observational
The Use of Major Depression Inventory (MDI) in Measuring Preoperative Depressive Symptoms in Breast Cancer Patients
NCT01284751CI-TRIAL-00004810completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to measure depressive symptoms in breast cancer patients before surgery with Major Depression Inventory (MDI). The investigators hypothesize that this patient group will not produce scores correlating to having a mild, moderate or severe depression even though they have just recently experienced a major life crisis by receiving a malignant diagnosis.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Depression | — | UNRESOLVED | — |
| Depressive Symptoms | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MDI - self-rating inventory | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Breast cancer patients
- description
- Patients aged 30-70 years having a lumpectomy or mastectomy at the Department of Breast Surgery at Herlev Hospital, Copenhagen, Denmark.
- interventionNames
- Other: MDI - self-rating inventory
Primary outcomes (1)
- measure
- Depressive symptoms
- timeFrame
- Approximately one week before surgery
- description
- Total score on the Major Depression Inventory. When used as a diagnostic instruemtn patients witll according to the ICD-10 algorhythym be classified as mild, moderate or severe depression or no depression.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 30 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Women aged 30-70 years old, who are undergoing a lumpectomy or mastectomy * ASA I-III Exclusion Criteria: * Planned or ongoing preoperative chemotherapy * Known and treated sleep apnea syndrome * Insulin treated diabetes mellitus * Known or previous treated depressive illness or bipolar disorder * Known autoimmune disease * Incompensated cirrhosis * Other previous or ongoing cancer * Known medically treated sleep disorder (insomnia, restless legs etc) * Shift-work or night-work * Daily alcohol intake of more than 5 units * Preoperative treatment with psychopharmacological drugs, opioids or anxiolytics * Predicted bad compliance * Pregnant or breast feeding * Preoperative MMSE score less than 24
References
Publications (3)
- BACKGROUNDOlsen LR, Jensen DV, Noerholm V, Martiny K, Bech P. The internal and external validity of the Major Depression Inventory in measuring severity of depressive states. Psychol Med. 2003 Feb;33(2):351-6. doi: 10.1017/s0033291702006724. PMID 12622314
- BACKGROUNDBech P, Rasmussen NA, Olsen LR, Noerholm V, Abildgaard W. The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity. J Affect Disord. 2001 Oct;66(2-3):159-64. doi: 10.1016/s0165-0327(00)00309-8. PMID 11578668
- BACKGROUNDOlsen LR, Mortensen EL, Bech P. Prevalence of major depression and stress indicators in the Danish general population. Acta Psychiatr Scand. 2004 Feb;109(2):96-103. doi: 10.1046/j.0001-690x.2003.00231.x. PMID 14725589