Clinical trial · Observational
Patterns of Care in Hormone-receptor Positive, Advanced Breast Cancer
Patterns of Care in Hormone-Receptor Positive, Advanced Breast Cancer in Brazil: A Prospective, Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to characterize the current patterns of care for patients with hormone-receptor-positive, advanced breast cancer who have failed one prior endocrine therapy in Brazil. To investigate patient-related, disease-related and physician-related characteristics that correlate with the use of either endocrine treatment or chemotherapy in such patients. And to evaluate patients' understanding of the treatment options and their participation in the choice.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- To assess the treatment choice by the medical oncologist for each patient.
- timeFrame
- 12 months
Secondary outcomes (3)
- measure
- To assess determinants of treatment choice
- timeFrame
- 12 months
- measure
- To assess the duration of treatment with chemotherapy or endocrine therapy
- timeFrame
- 12 months
- measure
- To evaluate the rate of treatment continuation at 6 months
- timeFrame
- 12 months
- description
- Assess the profile of adverse events with each treatment modality and assess patient participation and understanding in treatment choice
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histological or cytological diagnosis of breast cancer * Postmenopausal status at the time of enrolment, according to the following definitions: * History of bilateral oophorectomy at any age * Proven hormonal menopause * Positive estrogen receptor (ER) and/or progesterone receptor (PR) by immuno * Failure of one previous endocrine therapy in the adjuvant or metastatic setting * Use of no more than one previous chemotherapy regimen in the neoadjuvant or adjuvant setting * Indication to receive chemotherapy or endocrine therapy Exclusion Criteria: * Inability to comply with the study protocol * Use of more than one previous endocrine therapy, regardless of the setting; -- Previous use of chemotherapy for metastatic disease * Use of neoadjuvant endocrine therapy as the only previous type of endocrine therapy * Serious medical, surgical or psychiatric comorbidity that, upon investigator's discretion, should preclude participation in the study.
References
Publications (0)
Data not yet available