Clinical trial · Interventional
The Impact of Different Anticoagulant Therapy on Hemorrhage and Coagulation After Thoracic Surgery
NCT01267305CI-TRIAL-00014370completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether the use of different dose of LMWH compared with fondaparinux for thromboprophylaxis is efficacious and safety after thoracic surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Neoplasms | Esophageal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Lung Neoplasms | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Venous Thromboembolism | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fondaparinux | Drug | — | UNRESOLVED |
| Nadroparin Calcium | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (6)
- type
- ACTIVE_COMPARATOR
- label
- lung lmwh1
- description
- use LMWH once daily after lung resection
- interventionNames
- Drug: Nadroparin Calcium
- type
- EXPERIMENTAL
- label
- lung lmwh2
- description
- use LMWH twice daily after lung resection
- interventionNames
- Drug: Nadroparin Calcium
- type
- EXPERIMENTAL
- label
- lung Fondaparinux
- description
- use Fondaparinux once daily after lung resection
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * clinical diagnosis of esophageal carcinoma and planned for esophagectomy * clinical diagnosis of lung carcinoma and planned for lung resection * general anesthesia combined with epidural anesthesia Exclusion Criteria: * blood clotting disfunction before surgery * anticoagulating or antiplatelet history before surgery * low blood platelets count * hemorrhagic disease * cerebral hemorrhage * cerebral,spinal,ophthalmologic operation history * peptic ulcer * bleeding\>400ml in operation * bleeding\>100ml/h after operation * blood transfusion in or after operation * severe renal or liver disfunction * severe hypertension
References
Publications (0)
Data not yet available
No reference posted for this study.