Clinical trial · Interventional
MC-5A for Chemotherapy Induced Peripheral Neuropathy
Treatment of Painful Chemotherapy -Induced Peripheral Neuropathy With the MC-5A Pain Therapy Medical Device, a Randomized, Double-Blind, Sham-Controlled Clinical Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Painful chemotherapy induced peripheral neuropathy (CIPN) is a common complication of cancer therapy with few treatment options. CIPN is a complex side effect that varies between individuals and can be difficult to describe, difficult to treat and can significantly effect quality of life for patients. The purpose of this study is to determine if patients with painful CIPN will have a decrease in pain scores after treatment with the MC-5A device.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neuropathy, Paraneoplastic | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MC-5A | Device | — | UNRESOLVED |
| Sham device | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- SHAM_COMPARATOR
- label
- Sham device
- description
- Sham therapy device to area of painful chemotherapy induced peripheral neuropathy (CIPN) for 45 minutes daily x 10 days
- interventionNames
- Drug: Sham device
- type
- ACTIVE_COMPARATOR
- label
- MC-5A treatment
- description
- MC-5A therapy to the area of painful CIPN for 45 minutes daily for a total of 10 days.
- interventionNames
- Device: MC-5A
Primary outcomes (1)
- measure
- Change in Mechanical Visual Analog Scale (mVAS) Using Quantitative Sensory Pain Testing (QSPT)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * painful peripheral neuropathy resulting from chemotherapy * pain must be present for minimum of 6 months * must be able to read/understand English * stable analgesics regimens allowed (no change for past 7 days) Exclusion Criteria: * painful peripheral neuropathy that is not the result of chemotherapy * pregnant women * patients unable to wean off anti-epileptics * patients currently receiving chemotherapy known to cause peripheral neuropathy * patients with pacemakers or implanted defibrillators * patients with vena cava or aneurysm clips * patients with a history of epilepsy
References
Publications (0)
Data not yet available