Clinical trial · Observational
F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases
18F-Fluoride PET Bone Scans Versus Traditional 99mTc-MDP Gamma Camera Bone Scans for the Diagnosis of Bone Metastases: a Blinded, Prospective Trial
NCT01254929CI-TRIAL-00044144completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to compare 18F-Fluoride PET bone scans to traditional 99mTc-MDP bone scan to determine if one is better for diagnosing bone metastases.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Metastases | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| F-18 PET bone scan | Device | — | UNRESOLVED |
| Tc-99m bone scan | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- F-18 PET bone scan group
- description
- Patients with a diagnosis of cancer and clinical concern for bone metastases. They will undergo an F-18 PET bone scan for diagnostic imaging.
- interventionNames
- Device: F-18 PET bone scan
- label
- Tc-99m MDP bone scan group
- description
- Patients with a diagnosis of cancer and clinical concern for bone metastases. They will undergo a Tc-99m MDP bone scan for diagnostic imaging.
- interventionNames
- Device: Tc-99m bone scan
Primary outcomes (1)
- measure
- Accurate identification of bone metastases
- timeFrame
- Upon study completion (2-3 years)
- description
- Individual subjects will be reviewed 6-12 months after their bone scans, utilizing all clinical and imaging data available, to determine diagnostic accuracy of each bone scan.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient has cancer * Has been referred for evaluation of bone metastases * Patient or patient's legal representative can understand and consent to enrollment in the study * Must be 18 years or older * Can remain still during the scan (approximately one hour) * Patient has Medicare Exclusion Criteria: * Patient does not have Medicare * Under the age of 18 * Cannot lie still for the necessary time
References
Publications (0)
Data not yet available
No reference posted for this study.