Clinical trial · Interventional
Prognostic Impact of Anatomical Resection Vs. Non-anatomical Resection for HCC
Anatomical Liver Resection by Means of Ultrasound-guided Vessel Compression Versus Non-anatomical Resection for Hepatocellular Carcinoma: A Randomized Controlled Trial
NCT01236989CI-TRIAL-00004094ARversusNARunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Prognostic impact of AR vs NAR
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Disease-Free Survival | — | UNRESOLVED | — |
| Overall Survival | — | UNRESOLVED | — |
| Patients Affected by Hepatocellular Carcinoma | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| anatomical liver resection | Procedure | — | UNRESOLVED |
| Non-anatomical liver resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Anatomical resection
- interventionNames
- Procedure: anatomical liver resection
- type
- ACTIVE_COMPARATOR
- label
- Non-anatomical resection
- interventionNames
- Procedure: Non-anatomical liver resection
Primary outcomes (1)
- measure
- the prognostic impact of anatomical resection by means of intraoperative ultrasound (IOUS) guided vessel compression versus nonanatomical resection in terms of disease free and overall survival
- timeFrame
- 5-years
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * patient affected by single HCC * patients in whom liver resection is indicated * HCC without vascular invasion and/or thrombosis Exclusion Criteria: * multinodular HCC * metastatic disease * spontaneous tumor rupture
References
Publications (3)
- BACKGROUNDHasegawa K, Kokudo N, Imamura H, Matsuyama Y, Aoki T, Minagawa M, Sano K, Sugawara Y, Takayama T, Makuuchi M. Prognostic impact of anatomic resection for hepatocellular carcinoma. Ann Surg. 2005 Aug;242(2):252-9. doi: 10.1097/01.sla.0000171307.37401.db. PMID 16041216
- BACKGROUNDTorzilli G, Procopio F, Cimino M, Del Fabbro D, Palmisano A, Donadon M, Montorsi M. Anatomical segmental and subsegmental resection of the liver for hepatocellular carcinoma: a new approach by means of ultrasound-guided vessel compression. Ann Surg. 2010 Feb;251(2):229-35. doi: 10.1097/SLA.0b013e3181b7fdcd. PMID 19838106
- BACKGROUNDTorzilli G, Makuuchi M. Ultrasound-guided finger compression in liver subsegmentectomy for hepatocellular carcinoma. Surg Endosc. 2004 Jan;18(1):136-9. doi: 10.1007/s00464-003-9024-x. Epub 2003 Nov 21. PMID 14625736