Clinical trial · Interventional
EBUS Guided Cryo Biopsy of Solitary Pulmonary Nodules
NCT01221493CI-TRIAL-00004026unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To proof the feasibility and safety of EBUS guided transbronchial cryo biopsies in peripheral lung lesions
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solitary Pulmonary Nodule | — | UNRESOLVED | — |
| Yield of Cryo Biopsy in Lung Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cryo biopsy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Cryo biospy
- interventionNames
- Procedure: Cryo biopsy
Primary outcomes (1)
- measure
- Safety
- timeFrame
- 24 h after intervention
- description
- Number of Participants with Adverse Events as a Measure of Safety Detailed analysis of number of Pneumothoraces and number of bleeding complication
Secondary outcomes (1)
- measure
- Efficacy
- timeFrame
- 48 h after intervention
- description
- Diagnostic yield of the different biopsy techniques in establishing a specific diagnosis of the lesion
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * solitary pulmonary nodule \< 4 cm * no endobronchial lesion * indication for bronchoscopy Exclusion Criteria: * coagulopathy * pulmonary hypertension * pregnancy
References
Publications (5)
- BACKGROUNDEberhardt R, Kahn N, Gompelmann D, Schumann M, Heussel CP, Herth FJ. LungPoint--a new approach to peripheral lesions. J Thorac Oncol. 2010 Oct;5(10):1559-63. doi: 10.1097/JTO.0b013e3181e8b308. PMID 20802352
- BACKGROUNDEberhardt R, Gompelmann D, Herth FJ. Electromagnetic navigation in lung cancer: research update. Expert Rev Respir Med. 2009 Oct;3(5):469-73. doi: 10.1586/ers.09.36. PMID 20477337
- BACKGROUNDEberhardt R, Morgan RK, Ernst A, Beyer T, Herth FJ. Comparison of suction catheter versus forceps biopsy for sampling of solitary pulmonary nodules guided by electromagnetic navigational bronchoscopy. Respiration. 2010;79(1):54-60. doi: 10.1159/000232394. Epub 2009 Jul 31. PMID 19648733
- BACKGROUNDEberhardt R, Kahn N, Herth FJ. 'Heat and destroy': bronchoscopic-guided therapy of peripheral lung lesions. Respiration. 2010;79(4):265-73. doi: 10.1159/000284015. Epub 2010 Feb 10. PMID 20203535
- DERIVEDSchuhmann M, Bostanci K, Bugalho A, Warth A, Schnabel PA, Herth FJ, Eberhardt R. Endobronchial ultrasound-guided cryobiopsies in peripheral pulmonary lesions: a feasibility study. Eur Respir J. 2014 Jan;43(1):233-9. doi: 10.1183/09031936.00011313. Epub 2013 Jul 30. PMID 23900983