Cancer Survival Through Weight Loss and Exercise

Inclusion Criteria:

* Women between the ages of 30 and 75.
* Positive history of breast cancer treatment completed at least 2 months but no longer than 36 months prior to randomization.
* BMI ≥ 25 kg/m2 and ≤ 45 kg/m2
* Not involved in regular physical activity or weight loss management programs.
* Stage I, II or IIIa breast cancer with good prognosis.

Exclusion Criteria:

* Presence of any co-morbidities including cardiovascular disease or diabetes
* Fasting triglycerides \> 500 mg/dl.
* Consume more than 14 alcoholic beverages per week.
* A history of drug abuse, or excess alcohol consumption (40g/day)6.
* Currently dieting or engaging in any activity with the goal of losing weight.
* Significant intentional weight loss in the past year (\> 50 lbs in the past year) or current use of weight loss medications.
* History of gastrointestinal bypass or other bariatric surgery in the last 3 years.
* Pregnant or plan on becoming pregnant in the next 12 months.
* Factors that may limit adherence to intervention or affect conduct of the trial.
* Unable or unwilling to communicate with staff, to provide written informed consent, or accept the randomized assignment.
* Failure to complete run-in and baseline testing.
* Lack support from health care provider or family members.
* Other temporary intervening event, such as sick spouse, bereavement, or recent move.
* Any other medical condition or disease that is life threatening or that can interfere with or be aggravated by exercise.
* Current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder.
* Any other condition, which, in the opinion of the investigators would impede competence or compliance or possibly hinder completion of the study.