Clinical trial · Observational
Changes in Liver Function After Stereotactic Body Radiation Therapy Measured by PET/CT
Radiation Induced Change of Liver Function Measured by Uptake of the Galactose Analogue FDGal and PET/CT
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients treated with stereotactic radiotherapy for liver tumors undergo PET/CT using the galactose analogue 18-F-deoxy-galactose (FDGal) before and after radiotherapy. This technique provides volumetric mapping of liver function and it allows quantisation of liver function. The method may be used for selection of patients for stereotactic radiotherapy of liver tumors, for determination of radiation induced liver dysfunction and may be included into the treatment planning process of stereotactic radiotherapy.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cholangiocarcinoma | Cholangiocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Metastases | — | UNRESOLVED | — |
| Stereotactic Body Radiotherapy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Measuring liver function by PET/CT | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Liver tumors
- description
- Patients where stereotactic body radiation therapy is planned for primary or metastatic liver tumors.
- interventionNames
- Other: Measuring liver function by PET/CT
Primary outcomes (1)
- measure
- Uptake of FDGal
- timeFrame
- Before, 1 month and 3 months after stereotactic radiotherapy
- description
- Volumetric uptake of FDGal can be measured is measured by PET/CT
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * liver tumor * referred for stereotactic radiation therapy * age \> 18 years Exclusion Criteria: * Impaired kidney function * Pregnancy
References
Publications (0)
Data not yet available