Clinical trial · Observational
The Clinical,Radiologic,Pathologic and Molecular Marker Characteristics of Pancreatic Cysts Study
The Clinical,Radiologic, Pathologic and Molecular Marker Characteristics of Premalignant and Malignant Pancreatic Cysts Study
NCT01202136CI-TRIAL-00104164PCystcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim is to propose and prospectively validate a diagnostic approach and model for prediction of mucinous versus non-mucinous, and malignant versus non-malignant pancreatic cysts using a combination of clinical, radiologic, and biomarker characteristics.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Pancreatic Cysts | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Pancreatic cysts
- description
- patients referred to Johns Hopkins Hospital for evaluation and or treatment for 1 or more pancreatic cysts
Primary outcomes (1)
- measure
- Prevalence and incidence of malignant pancreatic cysts
- timeFrame
- 3-6 years
- description
- 1)to determine the prevalence and incidence of malignancy in pancreatic cysts according to cyst size and concerning features
Secondary outcomes (6)
- measure
- Biomarkers to predict type of pancreatic cyst
- timeFrame
- 3-6 years
- description
- To collect tissue samples (cyst fluid and blood) for research on molecular markers in pancreatic cysts
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Adult patients age 18 years and older 2. Referred for assessment of one or more pancreatic cyst. Exclusion Criteria: 1. Medically ill patients with ASA class 4 or greater. 2. History of chronic kidney disease with a serum creatinine \> 2.0 mg/dl or estimated glomerulofiltration rate (eGFR) \< 30 ml/min, dialysis patients, acute renal failure, cirrhosis of the liver, chronic hepatitis, prior nephrectomy or kidney or liver transplantation. 3. History of moderate (generalized hives) or severe (facial swelling, airway reaction) reaction to intravenous radiographic contrast material. 4. History of obstruction in the upper GI tract such as esophageal or pyloric stricture, which would not allow passage of an endoscope. 5. Bleeding diathesis (clotting problems) or a history of thrombocytopenia (low platelet count \<50,000). 6. Inability to provide informed consent. 7. Pregnancy or lactation.
References
Publications (0)
Data not yet available
No reference posted for this study.