Clinical trial · Observational
Early Increase in Blood Supply in Patients With Barrett's Esophagus
Detectable Esophageal Early Increase in Blood Supply (EIBS) in Patients With Barrett's Esophagus
NCT01188980CI-TRIAL-00021886EIBS in BEcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine if early Barrett's specialized intestinal metaplasia can be detected by measuring early increased blood supply of the esophageal tissue, with 4 Dimensional Elastic Light-Scattering Fingerprinting, (4D-ELF) technology in real time.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Barrett's Esophagus | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (3)
- label
- NoBE (control)
- label
- BE without dysplasia
- label
- BE with dysplasia
Primary outcomes (1)
- measure
- determine if early increase blood supply (EIBS)can predict presence of Dysplasia
- timeFrame
- 10 minutes during standard upper endoscopy
- description
- To determine if early increase blood supply (EIBS), as measured in Barrett's glandular mucosa segment, can predict the presence of Dysplasia in patients with known diagnosis of Barrett's esophagus (BE).
Secondary outcomes (1)
- measure
- determine if EIBS can predict presence of BE in patients undergoing upper endoscopy
- timeFrame
- 10 minutes
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * age 18 years or older, * informed written consent, * patient scheduled for previously planned upper endoscopy Exclusion Criteria: * liver disease; * gastric antral vascular ectasia (GAVE);any known non-esophageal aerodigestive malignancy; * severe cardiopulmonary disease precluding endoscopy; presence of conditions not allowing biopsy (e.g. coagulation disorder); * known familial polyposis syndrome (FAP, HNPCC, Juvenile polyposis, etc.); * known pregnancy or sexually active females of childbearing age who are not practicing an accepted form of birth control.
References
Publications (0)
Data not yet available
No reference posted for this study.