Clinical trial · Observational
The Value of Polyp Surface Pattern Recognition in the Identification of Neoplasia: a Prospective Study
Polyp Surface Pattern Recognition in the Identification of Neoplastic Polyps
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
It is current practice to remove any polyps found during colonoscopy. This is because adenomatous polyps have the potential to turn into cancer. However, a proportion of polyps \<10mm in size are hyperplastic, which cannot turn into cancer. Current practice requires these to be removed, as it is traditionally felt that they cannot be separated clinically from adenomas. This increases the risk of perforation and results in a significant cost in processing the samples. However, it has been suggested that it is possible to differentiate neoplastic from non neoplastic lesions using skills in polyp surface pattern recognition. If this is the case the investigators may be able to reduce the need for polypectomy The investigators believe that it is possible to tell the difference between polyps with cancerous potential and those that are harmless by assessment of surface patterns. This may enable us to improve the investigators clinical decisions when assessing polyps during colonoscopy, and reduce the number of unnecessary polypectomys being performed.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Polyps | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Observation of surface patterns of polyps | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- In vivo diagnosis
- description
- Patients undergoing colonoscopy where one or more polyps up to 10mm in size are found.
- interventionNames
- Other: Observation of surface patterns of polyps
Primary outcomes (1)
- measure
- The accuracy of predicted in-vivo polyp histology
- timeFrame
- 9 months
Secondary outcomes (7)
- measure
- • Sensitivity of white light endoscopy in predicting histology
- timeFrame
- 9 months
- measure
- specificity of white light endoscopy in predicting histology
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients found to have polyps up to 10 mm in size Exclusion Criteria: * Patient preference Clinicians judgement Obvious cancers Ulcerated polyps
References
Publications (0)
Data not yet available