Clinical trial · Interventional
Regional Anesthesia and Lung Cancer Recurrence
The Effect of Adding Intraoperative Regional Anesthesia on Cancer Recurrence in Patients Undergoing Lung Cancer Resection
NCT01179308CI-TRIAL-00023886terminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): The principal investigator decided to close this study site.
Summary
Brief summary (as posted)
Test the effect of combined regiona/general anesthesia on lung cancer recurrence compared to general anesthesia alone.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Balanced general anesthesia and postoperative opioids | Other | — | UNRESOLVED |
| General-epidural anesthesia | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- General-epidural anesthesia
- description
- Epidural and general anesthesia
- interventionNames
- Other: General-epidural anesthesia
- type
- ACTIVE_COMPARATOR
- label
- General anesthesia
- description
- General anesthesia alone
- interventionNames
- Other: Balanced general anesthesia and postoperative opioids
Primary outcomes (1)
- measure
- disease-free survival
- timeFrame
- up to 5 years after surgery
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Primary non-small cell lung cancer (stage 1-3) as determined according to the IASLC Lung Cancer Staging Project; * Scheduled for potentially curative tumor resection; * Written informed consent, including willingness to be randomized to epidural anesthesia/analgesia plus general anesthesia or to general anesthesia and postoperative opioid analgesia. Exclusion Criteria: * Any contraindication to epidural anesthesia, (including coagulopathy, abnormal anatomy). * Any contraindication to midazolam, propofol, sevoflurane, fentanyl, morphine, or hydromorphone. * Age \< 18 or \> 85 years old. * Other cancer not believed by the attending surgeon to be in long-term remission.
References
Publications (0)
Data not yet available
No reference posted for this study.