Clinical trial · Observational
A Retrospective Analysis of Statin Use and Outcome After Thoracic Cancer Surgery
NCT01169051CI-TRIAL-00113100completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
There is data to support an association between impaired preoperative endothelial function and adverse postoperative outcome. This study will investigate the potential association between perioperative statin use and improved perioperative and long-term cancer outcome amongst thoracic surgery patients undergoing lung or esophageal resection.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophagectomy | — | UNRESOLVED | — |
| Pulmonary Lobectomy | — | UNRESOLVED | — |
| Pulmonary Pneumonectomy | — | UNRESOLVED | — |
| Pulmonary Wedge Resection | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Thoracic sugery statins
- label
- Thoracic surgery non-statins
Primary outcomes (1)
- measure
- Effect of perioperative statin use on in-hospital morbidity after thoracic cancer surgery
Secondary outcomes (3)
- measure
- Effect of perioperative statin use on the development of Major Adverse Pulmonary Events (MAPE)
- timeFrame
- 30 days after initial surgery
- description
- Includes acute lung injury, acute respiratory distress syndrome, pulmonary embolus, respiratory failure requiring mechanical ventilation and pneumonia
- measure
- Effect of perioperative statin use and the development of Major Adverse Cardiac Events (MACE)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: This study is a retrospective chart review of adult thoracic surgery patients who underwent: * Esophagectomy * Pulmonary wedge resection * Pulmonary lobectomy * Pulmonary pneumonectomy Data collected will be from January 1, 2007 forward Exclusion Criteria: None
References
Publications (0)
Data not yet available
No reference posted for this study.