Clinical trial · Observational
PET-CT and Circulating Tumor Cells in Colorectal Cancer
Identifying an Early Indicator of Drug Efficacy in Patients With Advanced Colorectal Cancer - a Prospective Evaluation of Circulating Tumor Cells, Positron-emission Tomography Scan and RECIST Criteria
NCT01163305CI-TRIAL-00027429completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to identify an early indicator of drug efficacy in patients with advanced colorectal cancer - a prospective evaluation of circulating tumor cells, positron-emission tomography scan and RECIST criteria.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Metastasis | Colorectal Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Chemotherapy | Drug | Chemotherapy | ALIAS |
Design
Arms and outcomes
Arms (1)
- label
- metastatic colorectal cancer
- interventionNames
- Drug: Chemotherapy
Primary outcomes (1)
- measure
- Tumor metabolic response via FDG-PET at 4 weeks after chemotherapy
- timeFrame
- 2 years
Secondary outcomes (5)
- measure
- Overall survival
- timeFrame
- 4 years
- measure
- Progression-free survival
- timeFrame
- 4 years
- measure
- serum carcinoembryonic antigen (CEA) level
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Metastatic colorectal cancer patients not received prior drug treatment for metastatic CRC * Age \>= 18 years * (ECOG) performance status of 0-2 * Measurable tumor sites by RECIST criteria * Adequate bone marrow, renal \& hepatic functions Exclusion Criteria: * Patients with diabetes mellitus * presence of hyperglycemia * Pregnant or lactating patients
References
Publications (0)
Data not yet available
No reference posted for this study.