Clinical trial · Observational
Specimen X-Rays of Removed Axillary Lymph Nodes to Guide Pathological Sampling
Specimen X-Rays of Removed Axillary Lymph Nodes to Guide Pathological Sampling (GPS)
NCT01156454CI-TRIAL-00025260GPScompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
X-ray mapping of sentinel lymph nodes and/or axillary tissue will assist pathologists in their ability to identify the number and location of lymph nodes as well as more accurately section lymph nodes contained in surgical specimens.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| X-ray | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Surgery followed by x-ray assessment
- description
- After nodes are removed they are taken to radiology to be x-rayed
- interventionNames
- Procedure: X-ray
Primary outcomes (2)
- measure
- Identification of lymph nodes
- timeFrame
- Within the first 30 minutes after specimen is removed from the body
- description
- To determine if plain x-ray films obtained from the sentinel node/axillary dissection specimen can facilitate the identification of the lymph nodes and increase the average number of lymph nodes recovered by the pathologist.
- measure
- Identification of affected area in node
- timeFrame
- Within the first 30 minutes after specimen is removed from the body
- description
- To determine whether plain x-ray films obtained from the sentinel node/axillary dissection specimen can help direct the pathologist to the correct part of the node (the portion containing disease) to sample.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Males or females of all races and ethnicities * ≥ 18 years of age * Must be scheduled for breast cancer surgery which includes a sentinel lymph node biopsy and/or axillary dissection Exclusion Criteria: • Any person whose final pathology could be compromised in any way by the X-ray procedure
References
Publications (1)
- RESULTJohnson CB, Korourian S, Badgwell BD, Fincher RL, Dell CM, Don Bice C, Boneti C, Westbrook KC, Klimberg VS. Sensitivity of axillary specimen x-ray to predict nodal count and positivity. Ann Surg Oncol. 2011 Oct;18(11):3181-6. doi: 10.1245/s10434-011-1959-x. Epub 2011 Aug 23. PMID 21861231