Clinical trial · Interventional
Trial to Evaluate Single- and Double- Freeze Cryotherapy in the Prevention of Cervical Neoplasia
Randomised Intervention Trial to Evaluate Single- and Double- Freeze Cryotherapy in the Prevention of Cervical Neoplasia
NCT01145781CI-TRIAL-00032732completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate whether single- and double-freeze cryotherapy techniques have similar efficacy in controlling different grades of cervical intraepithelial neoplasia (CIN), and have similar side effects and complications.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Intraepithelial Neoplasia | Cervical Intraepithelial Neoplasia | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cryotherapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Single-freeze cryotherapy
- description
- Arm 1 Single-freeze technique; 3 minutes of freeze and 5 minutes of thaw.
- interventionNames
- Procedure: Cryotherapy
- type
- ACTIVE_COMPARATOR
- label
- Double-freeze cryotherapy
- description
- Arm 2 Double-freeze technique: 3 minutes of freeze and 5 minutes of thaw and cycle repeated once again.
- interventionNames
- Procedure: Cryotherapy
Primary outcomes (1)
- measure
- The primary end point is the cure rate at the end of one year
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 25 Years
- Maximum age
- 64 Years
Show eligibility criteria text
Inclusion Criteria Apparently healthy women aged 25 to 64 yrs with following criteria will be eligible to participate in the study. 1. Histological confirmation of ASCUS -H, CIN I, CIN II and CIN III lesions. 2. The lesion confined to ecto cervix only. 3. No obvious cervical and vaginal infection. 4. Women in proliferative phase of menstrual cycle or post menopausal cases. 5. Negative endo cervical curettage. Exclusion criteria Women less than 25 and more than 64 years will not be enrolled.
References
Publications (0)
Data not yet available
No reference posted for this study.