Clinical trial · Interventional
Compound Herbal Formula (TPE-1) for Leukopenia and Cancer-related Fatigue in Breast Cancer Patients With Radiotherapy
The Effects of Compound Herbal Formula(TPE-1) for Leukopenia and Cancer-related Fatigue in Breast Cancer Patients With Radiotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Many breast cancer patients will taking Chinese herbal medicine during receiving radiotherapy. The investigators conducted the pilot study showing Compound Herbal Formula (TPE-1) have the effect of improving the fatigue and leukopenia during radiotherapy. So the investigators designed this double blind and controlled trial to evaluate whether TPE-1 have the effects for leukopenia and cancer-related fatigue in breast cancer patients with radiotherapy. From our initial observation for 2 years, TPE-1 is safety. The study is also designed to evaluate the safety when patients taking this formula.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Chinese Herbal Medicine | — | UNRESOLVED | — |
| Radiotherapy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Chinese herbal medicine decoction | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- PLACEBO_COMPARATOR
- label
- herbal A
- description
- dilute of (TPE-1) decoction.
- interventionNames
- Drug: Chinese herbal medicine decoction
- type
- EXPERIMENTAL
- label
- herbal B
- description
- TPE-1 decoction (100 ml)
- interventionNames
- Drug: Chinese herbal medicine decoction
Primary outcomes (1)
- measure
- the % change of white blood cell(WBC) count
- timeFrame
- 6 weeks
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * breast cancer * age between 18 to 70 yrs * finished chemotherapy (adriamycin ), will receiving radiotherapy * Chinese population * KP$ between 40-100 * ECOG \< 2 * WBC \>4X10(9)／L and Hb \> 10g/dl * Assigned informed concent. Exclusion Criteria: * receiving operation during 14 days * blood transfusion during one month. * ALT \>100mg/dL * Creatinine \>2.0mg/dL * Total bilirubin \>2.0mg/dL * Infection * prolation * Taking anti-seizure , psychological drugs or any drugs not suitable patients * AIDS or any disease diagnosed by physician and not suitable patients.
References
Publications (0)
Data not yet available