Clinical trial · Interventional
Development of a Biomarker for Dietary Furanocoumarins
NCT01142037CI-TRIAL-00015450completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Certain plant foods are high in furanocoumarins. Test tube and animal studies suggest that furanocoumarins may help prevent cancer. It is difficult to determine in humans if furanocoumarins do prevent cancer because there isn't an objective way to tell who has eaten these compounds. This study will develop a urine test to determine if an individual ate foods that contain furanocoumarins.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Healthy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cooked parsnips with parsley | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Furanocoumarin
- description
- Includes participants first refraining from eating foods with furanocoumarins for one week, followed by 2 weeks of increasing furanocoumarin consumption. Participants will be asked to consume cooked parsnips and parsley.
- interventionNames
- Dietary Supplement: Cooked parsnips with parsley
Primary outcomes (1)
- measure
- Urinary Biomarker Results for Dietary Furanocoumarins
- timeFrame
- Week 1
- description
- determine the optimal conditions for furanocoumarin identification and quantification in human urine
Secondary outcomes (1)
- measure
- Mean Concentration of Dietary Furanocoumarin in Urine
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Must be at least 18 years of age * Healthy Exclusion Criteria: * History of gastrointestinal, hepatic or renal disorder * Currently taking any prescription or over-the-counter medication * Currently taking any herbal supplement * Pregnant or lactating * Allergies to foods that will be used (parsnips and parsley)
References
Publications (0)
Data not yet available
No reference posted for this study.