Clinical trial · Observational

Biomarkers in Tissue Samples From Patients With Ductal Breast Carcinoma in Situ

A Correlative Science Study for ECOG E5194

NCT01132560CI-TRIAL-00027661completedClinicalTrials.gov clinicaltrialsPublishedExplore in graph →

Summary

Brief summary (as posted)

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is studying biomarkers in tissue samples from patients with ductal breast carcinoma in situ.

Conditions

Conditions (1)

Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.

Condition (as posted)	Mapped entity	Match	Confidence
Breast Cancer	Malignant Breast Neoplasm	CURATED_EXACT	0.92

Interventions

Interventions (4)

Intervention	Type	Mapped drug	Match
gene expression analysis	Genetic	—	UNRESOLVED
laboratory biomarker analysis	Other	—	UNRESOLVED
reverse transcriptase-polymerase chain reaction	Genetic	—	UNRESOLVED
RNA analysis	Genetic	—	UNRESOLVED

Design

Arms and outcomes

Arms (0)

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Primary outcomes (1)

measure
Ipsilateral local failure (first event of invasive or DCIS recurrence)
timeFrame
1 month

Secondary outcomes (1)

measure
Contralateral breast cancer (invasive or DCIS)
timeFrame
1 month

Eligibility

Eligibility (as posted)

Sex: Female
Minimum age: 18 Years
Maximum age: 120 Years

Show eligibility criteria text

DISEASE CHARACTERISTICS:

* Diagnosis of ductal breast carcinoma in situ
* Enrolled on clinical trial ECOG-E5194

  * Local surgery without radiotherapy
  * Treated or not treated with tamoxifen
* Available tissue samples
* Hormone receptor status not specified

PATIENT CHARACTERISTICS:

* Menopausal status not specified

PRIOR CONCURRENT THERAPY:

* See Disease Characteristics

References

Publications (0)

Data not yet available

No reference posted for this study.