Clinical trial · Interventional
Proton Radiotherapy for Recurrent Tumors
Retreatment of Recurrent Tumors Using Proton Therapy
NCT01126476CI-TRIAL-00044813completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine the feasibility of using proton radiotherapy for reirradiation of recurrent malignancies.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tumors | Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Proton Radiotherapy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- small volume strata
- description
- 12 in small volume strata
- interventionNames
- Other: Proton Radiotherapy
- type
- ACTIVE_COMPARATOR
- label
- large volume strata
- description
- 12 in large volume strata
- interventionNames
- Other: Proton Radiotherapy
Primary outcomes (2)
- measure
- Feasibility of proton therapy
- timeFrame
- 90 days
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with histologically confirmed, non-CNS solid malignancies who have been previously radiated and have a tumor recurrence in or near prior radiation fields. Re-biopsy of the recurrence is not required and left to the discretion of the treating physician, although every effort should be made to confirm recurrence. * Patients must have a Karnofsky Performance Status of 60. Life expectancy of 3 months . * Age greater or equal to 18. * Patients must be able to provide informed consent. * Women of child bearing potential as long as she agrees to use a recognized method of birth control (e.g. oral contraceptive, IUD, condoms or other barrier methods, etc.) * Hysterectomy or menopause must be clinically documented. Exclusion Criteria: * Prior radiation treatment less than 3 months from planned start of re-irradiation of any part of the intended treatment volume. * Pregnant women, women planning to become pregnant and women that are nursing. * Actively being treated on any research study.
References
Publications (0)
Data not yet available
No reference posted for this study.