Clinical trial · Interventional
Lymphedema Therapy With Sound Wave Lymphatic Drainage
Efficacy of Low Frequency Sound Waves in the Treatment of Breast Cancer Related Lymphedema: a Cross-over Randomized Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Lymphedema is a frequent sequela of breast cancer treatment, that can develop up to 40% of patients. Lymphedema is the accumulation of protein-rich fluid (lymph) in the interstitial spaces of the affected body part due to a blockage or malfunction in the lymph system. It can appear in the arm, shoulder, breast, or thoracic area. Lymphedema swelling causes discomfort and sometimes disability. The treatment of lymphedema associated with breast cancer can include complex decongestive physiotherapy, compression therapy, therapeutic exercises, and pharmacotherapy. In this study two treatments will be compared to reduce lymphedema: the manual lymphatic drainage (standard care) versus the low frequency sound waves.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphedema | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| low frequency sound waves | Device | — | UNRESOLVED |
| Manual lymphatic drainage | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- manual lymphatic drainage
- description
- Application of manual lymphatic drainage
- interventionNames
- Procedure: Manual lymphatic drainage
- type
- EXPERIMENTAL
- label
- low frequency sound waves
- description
- Application of low frequency sound waves
- interventionNames
- Device: low frequency sound waves
Primary outcomes (1)
- measure
- Volume of lymphedema
- timeFrame
- 2 months
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Lymphedema presence at least for 1 year * No previous treatments for lymphedema in the last 6 months Exclusion Criteria: * Electronic devices or metalic implants * Cardiac failure or hypertension * Epilepsy * Local infection * Pregnancy * Thrombophlebitis
References
Publications (0)
Data not yet available