Clinical trial · Observational
Stool Testing for Pancreatic Cancer
Detection of Pancreatic Cancer and Pre-cancer by Stool DNA Testing: A Feasibility Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine if pancreatic cancer/pre-cancer can be detected in early stages through the molecular analysis of stool samples. Investigators hypothesize that analysis of stool samples using digital melt curve (DMC) analysis, can be used as a sensitive and specific method to detect the common genetic abnormalities present in pancreatic cancers and pre-cancerous lesions of the pancreas.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Control Group
- description
- Individual who has not had pancreatic cancer/IPMN; surgical resection for lesion of pancreas; history of colorectal, gastric cancer, esophageal, or head-and-neck cancer; administration of chemotherapy less than 1 week prior to enrollment; or an endoscopic procedure conducted less than 1 week prior to enrollment.
- label
- Diagnosis of Pancreatic Cancer/IPMN
- description
- Patients diagnosed with Pancreatic Cancer/Intraductal Papillary Mucinous Neoplasm who are scheduled for surgical resection.
Primary outcomes (1)
- measure
- Positive mutation rate in tumors/IPMN lesions vs. control
- timeFrame
- 30 days
- description
- The positive mutation rates in tumor or IPMN lesions and in matched controls will be assessed.
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years of age and older. * Tissue-confirmed or radiological evidence of either pancreatic adenocarcinoma or intrapapillary mucinous neoplasm(IPMN). * Scheduled for surgical resection of the adenocarcinoma or IPMN. * Able to give informed consent Exclusion Criteria: * History of colorectal, gastric cancer, esophageal, or head-and-neck cancer. * Endoscopic procedure conducted less than 1 week prior to enrollment. * Unwillingness or inability to sign informed consent.
References
Publications (0)
Data not yet available