Clinical trial · Interventional
Trial for Single Port Versus Conventional Laparoscopic Colectomy
A Randomized Controlled Trial Comparing the Outcomes of Patients Who Undergo Single Port Laparoscopic Colectomy and Conventional Laparoscopic Colectomy for Colonic Neoplasia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to compare the outcomes of patients who undergo single-port laparoscopic colectomy and conventional laparoscopic colectomy for colonic neoplasia (large polyp not amenable to endoscopic removal/ cancer) through a randomized controlled trial. After informed consent, patients will be randomized to have either conventional or single-port laparoscopic colectomy by a team of surgeons with good experience in laparoscopic colorectal surgery. Patients' demographic, operative detail and post-operative outcomes including operating time, blood loss, complications, pain score, analgesic requirement, resumption of gastrointestinal function and length of hospital stay will be recorded prospectively. The patients will be blinded to the type of treatment that they have received during the first three days after operation (post-operative pain and analgesic requirement will be recorded in these period). Patients will have long term up to record for cancer recurrence and survival. The results of two groups of patients will be compared scientifically to assess if single-incision laparoscopic colectomy results in any difference in outcomes when compared to conventional laparoscopic colectomy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Cancers | — | UNRESOLVED | — |
| Colonic Polyps | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional laparoscopic colectomy | Procedure | — | UNRESOLVED |
| Single port laparoscopic colectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Single-port laparoscopic colectomy
- interventionNames
- Procedure: Single port laparoscopic colectomy
- type
- ACTIVE_COMPARATOR
- label
- Conventinal laparoscopic colectomy
- interventionNames
- Procedure: Conventional laparoscopic colectomy
Primary outcomes (1)
- measure
- Post-operative pain on coughing
- timeFrame
- The first three days after operation
- description
- The patients will be blinded to the type of treatment that they have received during the first three days after operation. During these three days, the post-operative pain score on coughing and analgesic requirement will be recorded independently by the Pain team of Department of Anesthesia who is also blinded to the type of procedure.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 89 Years
Show eligibility criteria text
Inclusion Criteria: 1. Histologically proven neoplastic disease of colon (large polyps not amenable to endoscopic removal or cancer) 2. Age \>18 years 3. Informed consent obtained 4. American Society of Anesthesiologist class 1-3 Exclusion Criteria: 1. Evidence of local invasion on pre-operative imaging 2. Cancer of diameter greater than 5cm 3. Contraindication for laparoscopic surgery 4. Anticipated peritoneal adhesion from previous major abdominal surgery 5. Presence of bowel obstruction 6. Lesion in transverse colon or rectum 7. Anticipated high dependency unit or intensive care unit admission after operation
References
Publications (2)
- BACKGROUNDLaw WL, Fan JK, Poon JT. Single-incision laparoscopic colectomy: early experience. Dis Colon Rectum. 2010 Mar;53(3):284-8. doi: 10.1007/DCR.0b013e3181c959ba. PMID 20173474
- BACKGROUNDLaw WL, Fan JK, Poon JT. Single incision laparoscopic left colectomy for carcinoma of distal transverse colon. Colorectal Dis. 2010 Jul;12(7):698-701. doi: 10.1111/j.1463-1318.2009.02114.x. Epub 2009 Nov 6. PMID 19895602