Clinical trial · Interventional
Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer
Randomized Controlled Trial Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer
NCT01080547CI-TRIAL-00026820completedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A new notion"Fast Track Multi-Discipline Treatment" for colorectal cancer is thought with several benefits such as shorter hospitalization stay and less costs. This randomized study aims to compare the differences between conventional and Fast Track Multi-Discipline Treatment for colorectal cancer in hospitalization day, complications, costs and quality of life.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adverse Drug Event | — | UNRESOLVED | — |
| Complications | — | UNRESOLVED | — |
| Hospital Costs | — | UNRESOLVED | — |
| Length of Stay | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional Perioperative Treatment | Other | — | UNRESOLVED |
| Fast Track Perioperative Treatment | Other | — | UNRESOLVED |
| Laparoscopic Surgery for Colorectal Cancer | Procedure | — | UNRESOLVED |
| mFolfox6 chemotherapy | Drug | — | UNRESOLVED |
| Open Surgery for Colorectal Cancer | Procedure | — | UNRESOLVED |
| XELOX Chemotherapy | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Conventional Treatment （Laparoscopic）
- description
- Randomized group of patients receiving laparoscopic colectomy with conventional perioperative treatment and mFolfox6 chemotherapy.
- interventionNames
- Procedure: Laparoscopic Surgery for Colorectal Cancer
- Drug: mFolfox6 chemotherapy
- Other: Conventional Perioperative Treatment
- type
- ACTIVE_COMPARATOR
- label
- FTMD Treatment （Laparoscopic）
- description
- Randomized group of patients receiving laparoscopic colectomy with Fast Track Multi-Displine（FTMD）treatment and XELOX chemotherapy.
- interventionNames
- Procedure: Laparoscopic Surgery for Colorectal Cancer
- Drug: XELOX Chemotherapy
- Other: Fast Track Perioperative Treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients with pathologically confirmed colorectal cancer 2. Signed consent Exclusion Criteria: 1. Tumor can be resected by endoscopic mucosal resection(EMR) 2. History of malignancy 3. Bowel obstruction or intestinal perforation 4. Evidence of metastasis by physical examination, chest roentgenogram and computed tomography of liver and pelvis 5. Acute diseases and acute attack of chronic diseases 6. Psychiatric history 7. Deformity of spine 8. ASA score≥Ⅳ 9. Mid-low rectal cancer 10. Pregnant woman 11. Needing to use Chinese traditional patent drug
References
Publications (3)
- DERIVEDLi J, Kong XX, Zhou JJ, Song YM, Huang XF, Li GH, Ying XJ, Dai XY, Lu M, Jiang K, Fu DL, Li XL, He JJ, Wang JW, Sun LF, Xu D, Xu JY, Chen M, Tian Y, Li JS, Yan M, Yuan Y, Ding KF. Fast-track multidisciplinary treatment versus conventional treatment for colorectal cancer: a multicenter, open-label randomized controlled study. BMC Cancer. 2019 Oct 23;19(1):988. doi: 10.1186/s12885-019-6188-x. PMID 31647032
- DERIVEDXu D, Li J, Song Y, Zhou J, Sun F, Wang J, Duan Y, Hu Y, Liu Y, Wang X, Sun L, Wu L, Ding K. Laparoscopic surgery contributes more to nutritional and immunologic recovery than fast-track care in colorectal cancer. World J Surg Oncol. 2015 Feb 4;13:18. doi: 10.1186/s12957-015-0445-5. PMID 25649903
- DERIVEDZhou JJ, Li J, Ying XJ, Song YM, Chen R, Chen G, Yan M, Ding KF. Fast track multi-discipline treatment (FTMDT trial) versus conventional treatment in colorectal cancer--the design of a prospective randomized controlled study. BMC Cancer. 2011 Nov 24;11:494. doi: 10.1186/1471-2407-11-494. PMID 22111914