Clinical trial · Observational
Virtual Bronchoscopy Transbronchial Needle Aspiration(TBNA): a Proof of Concept Study
CT-PET Virtual Bronchoscopy Guided Transbronchial Needle Aspiration for Mediastinal Lymph Node Staging in Suspected Lung Cancer
NCT01077492CI-TRIAL-00008410terminatedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine wether CT-PET virtual bronchoscopy guided transbronchial needle aspiration is suitable for the investigation of mediastinal lymph nodes which is needed for correct staging of lung cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Virtual Bronchoscopy Navigation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Suspected mediastianl lymph nodes
- description
- Patients with (suspected) lung cancer requiring MLN staging after CT-PET during routine work-up according to existing staging guidelines.
- interventionNames
- Other: Virtual Bronchoscopy Navigation
Primary outcomes (1)
- measure
- Feasibility of VB in determining N2/N3 mediastinal lymph nodes
- timeFrame
- 1 year
- description
- Feasibility of virtual bronchoscopy in showing the presence or abscense of N2/N3 mediastinal lymph node (MLN) metastasis with accuracy of 0.6 in puncturing MLN \> 15 mm (CT images) and accuracy of 0.8 for MLN \< 15 mm in the second phase of the study.
Secondary outcomes (1)
- measure
- Duration of the session within the optimal time window of local anesthesia using lidocaine 1%; comparable to standard routine bronchoscopic procedure on an outpatient basis, i.e. not exceeding 30 minutes.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> 18 years * Proven or suspected lung cancer, base on clinical picture and/or CT-PET findings * Suspected involvement of mediastinal lymph nodes on CT-PET scan * Written informed consent Exclusion Criteria: * None
References
Publications (0)
Data not yet available
No reference posted for this study.