Clinical trial · Interventional
Resection of Colorectal Liver Metastases With or Without Routine Hilar Lymphadenectomy
Resection of Colorectal Liver Metastases With or Without Routine Hilar Lymphadenectomy - A Randomized Controlled Trial
NCT01073358CI-TRIAL-00030089RELYunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
It is uncertain, whether hilar lymphadenectomy should be performed routinely in patients undergoing resection of colorectal liver metastases. For this reason it is the aim of the present prospective randomized trial to evaluate, if routine lymphadenectomy reduces recurrent disease in patients undergoing resection of colorectal liver metastases.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Hepatic Metastases | Colorectal Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Routine hilar lymphadenectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Group A: No routine hilar lymphadenectomy
- description
- Resection of colorectal liver metastases without routine hilar lymphadenectomy
- type
- EXPERIMENTAL
- label
- Group B: Routine hilar lymphadenectomy
- description
- Hilar lymphadenectomy is performed before actual resection of the colorectal liver metastases.
- interventionNames
- Procedure: Routine hilar lymphadenectomy
Primary outcomes (1)
- measure
- rate of disease recurrence
- timeFrame
- 2 years after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients scheduled for curative (R0) resection * No evidence of extrahepatic disease * No history of previous hepatic lymphadenectomy * Age equal or greater than 18 years * Written Informed consent Exclusion Criteria: * Expected lack of compliance * Impaired mental state or language problems * History of another primary cancer, except: * Curatively treated in situ cervical cancer or curatively resected non-melanoma skin cancer * Other primary solid tumour curatively treated with no known active disease present and no treatment administered for ≥ 5 years prior to randomisation
References
Publications (0)
Data not yet available
No reference posted for this study.