Clinical trial · Interventional
Endoscopic Ethanol Ablation of Communicating Pancreatic Cystic Neoplasms
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): slow accural
Summary
Brief summary (as posted)
Pancreatic cysts are common, and some pancreas cysts have malignant potential. Usual treatment of these cysts is either observation or surgical removal of part or all of the pancreas. Minimally invasive treatment via endoscopy has been described, using endoscopic ultrasound (EUS) guided ethanol injections. Such studies exclude cysts that communicate with the main pancreatic duct, to avoid burning the main pancreatic duct with ethanol. In this study, pancreas cysts communicating with the main pancreas duct are treated with ethanol via endoscopic retrograde cholangiopancreatography (ERCP) and/or EUS.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplasms, Cystic, Mucinous, and Serous | Neoplasm | ONTOLOGY_EXACT | 0.85 |
| Pancreatic Neoplasms | Pancreatic Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Ultrasonography, Interventional | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EUS and/or ERCP with ethanol injections of pancreatic cyst | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Cyst ethanol lavage
- description
- Subjects receiving the study intervention
- interventionNames
- Procedure: EUS and/or ERCP with ethanol injections of pancreatic cyst
Primary outcomes (2)
- measure
- Occurrence of adverse events requiring treatment or hospitalization
- timeFrame
- 3 days, 30 days
- measure
- Decrease in volume of the pancreatic cyst by cross-sectional imaging studies (CT or MR) performed before and after treatment
- timeFrame
- 6 months, 12 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Presence of a pancreatic cystic lesion, at least 2 cm in maximum diameter * Cyst may communicate, or definitely communicates, with the pancreatic duct (based on prior CT, MR, ERCP, or EUS images) * Treatment of the cystic lesion is desired due to symptoms or concern for subsequent malignancy * Age at least 18 years * Able to give informed consent * Surgical treatment has been considered and a surgical consultation offered to the patient, OR the subject's cyst does not meet consensus criteria for surgical resection. (Current consensus criteria for resection are one or more of the following: cyst is symptomatic, ≥ 3 cm in diameter, contains a mural nodule, cytology of cyst fluid is positive for malignancy, or main pancreatic duct diameter is \> 6 mm.) Exclusion Criteria: * Known or suspected pregnancy, or nursing * History of pancreatitis within 3 months prior to study endoscopy procedures * Cyst has a primarily microcystic architecture on EUS
References
Publications (0)
Data not yet available