Clinical trial · Interventional
Omega-3 Fatty Acids and Chemotherapy-induced Neuropathy and Inflammation in Breast Cancer
The Effects of Omega-3 Fatty Acids on Chemotherapy-induced Neuropathy and Inflammation in Patients With Breast Cancer
NCT01049295CI-TRIAL-00005707unknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to assess the effects of n-3 fatty acids on taxane-induced neuropathy and neurotoxic inflammatory agents in patients suffering from invasive breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| corn oil pearls | Other | — | UNRESOLVED |
| oil fish | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- oil fish pearls
- description
- patients with invasive breast cancer who received 640 mg oil fish pearls 3 times a day
- interventionNames
- Dietary Supplement: oil fish
- type
- PLACEBO_COMPARATOR
- label
- placebo
- description
- patient with invasive breast cancer who received corn oil pearls as placebo 3 times a day
- interventionNames
- Other: corn oil pearls
Primary outcomes (1)
- measure
- The EMG-NCV test,The serum level of IL-1,IL-6,TNF-alpha and hs-CRP
- timeFrame
- first day and after 3 months (before chemotherapy with taxanes and at the end of the therapy
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 30 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Suffering from invasive breast cancer,not receiving any form of supplementations and oil fish Exclusion Criteria: * Suffering from the diseases leading to neuropathy, e.g.diabetes, hyperthyroidism, AIDS and primary neural diseases * Suffering from any other kind of malignancies * Receiving any chemotherapeutical agents in the past
References
Publications (1)
- DERIVEDGhoreishi Z, Esfahani A, Djazayeri A, Djalali M, Golestan B, Ayromlou H, Hashemzade S, Asghari Jafarabadi M, Montazeri V, Keshavarz SA, Darabi M. Omega-3 fatty acids are protective against paclitaxel-induced peripheral neuropathy: a randomized double-blind placebo controlled trial. BMC Cancer. 2012 Aug 15;12:355. doi: 10.1186/1471-2407-12-355. PMID 22894640