Clinical trial · Interventional
Partial Liver Radiotherapy for Unresectable Liver Metastases
Partial Liver Radiotherapy for Patients With Unresectable Colorectal Liver Metastases
NCT01048216CI-TRIAL-00003010unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to treat tumors in the liver that cannot be removed surgically and chemotherapy cannot control these tumors, using radiation therapy and a more precise delivery than has been used before.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Colorectal Liver Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| radiation therapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- To evaluate feasibility of conformal radiation therapy in patients with metastatic colorectal liver cancer and determine its safety
Secondary outcomes (3)
- measure
- To evaluate local control rate within irradiated fields
- measure
- To assess failure patterns and survival of patients treated with conformal liver radiation
- measure
- Set up verification with cone-beam CT (OBI on Boar Imager)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * liver metastases unequivocally seen on contrast enhanced CT and/or MRI from colon or rectal cancer, previously confirmed pathologically as adenocarcinoma * either 1) the tumor must be unresectable, 2) the patient must be medically inoperable, or 3) extra-hepatic metastases are present (making hepatic surgery an inappropriate treatment option) * good performance status (0-1) * Age \> 18 years. Adult patients of all ages, both sexes and all races will be included in this study. Female patients within reproductive years may not be, nor become, pregnant during participation in this study * life expectancy \> 3 months Exclusion Criteria: * patients with active hepatitis or clinically significant liver failure * patients receiving anticoagulation treatment with warfarin or heparin * prior radiation therapy to the right upper abdomen, precluding re-irradiation of the liver * clinically apparent ascites * central nervous system metastases
References
Publications (0)
Data not yet available
No reference posted for this study.