Clinical trial · Interventional
Exercise for Stable Myasthenia Gravis
Multi-modal Exercise Program for Chronic Stable Myasthenia Gravis
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Generalized fatigue in myasthenia gravis results in physical deconditioning that reduces fitness and increases risk of obesity, hypertension, elevated cholesterol and type 2 diabetes. This study will examine how active and fit are 30 individuals with chronic, generalized myasthenic subjects. This study will also determine whether a 3 month home exercise program with aerobic, resistive, and pulmonary training can improve physical activity, strength, fitness, lung function and reduce cardiovascular disease risk.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myasthenia Gravis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- exercise
- description
- Multimodal exercises that include walking, breathing exercises, dynamic balance, and core strengthening.
- interventionNames
- Other: Exercise
Primary outcomes (1)
- measure
- Cardiovascular Fitness, Economy of Gait, Physiologic Reserve
- timeFrame
- Baseline and 3 months
Secondary outcomes (7)
- measure
- Ambulatory function (6 minute walk, 5 day step activity and accelerometer data)
- timeFrame
- Baseline and 3 month
- measure
- Muscle strength by dynamometer
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * stable generalized myasthenia gravis * adults age 18-70 Exclusion Criteria: * already performing regular exercise * unstable angina * recent (\<3 month) myocardial infarction, stroke, hospitalization for major illness or major surgery * chronic pain or orthopedic condition restricting exercise * active cancer, excluding basal cell cancer * anemia (HCT \<30) * pregnancy * myasthenia gravis exacerbation in past 3 months
References
Publications (0)
Data not yet available