Clinical trial · Interventional
Feasibility Study Using the Xoft System for the Treatment of Endometrial Cancer
Feasibility Study Using the Xoft Axxent Electronic Brachytherapy System for the Treatment of Endometrial Cancer
NCT01045187CI-TRIAL-00007653completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Multicenter, non-randomized, feasibility study to evaluate the treatment and assess acute safety of the FDA Cleared Axxent Electronic Brachytherapy System and vaginal applicator for intracavitary vaginal cuff treatment according to the physician's current standard of care.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| brachytherapy | Radiation | — | UNRESOLVED |
| Xoft Axxent Electronic Brachytherapy System | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- endometrial cancer
- description
- Patients are treated with electronic brachytherapy for an FDA cleared indication.
- interventionNames
- Radiation: brachytherapy
- Radiation: Xoft Axxent Electronic Brachytherapy System
Primary outcomes (1)
- measure
- Assess Number of Patients Who Were Able to Complete Treatment Delivery Using the Axxent Electronic Brachytherapy System
- timeFrame
- through completion of radiation therapy
Secondary outcomes (2)
- measure
- Assess Acute Safety Outcomes in Patients During and After Vaginal Cuff Brachytherapy Treatment With the Axxent Electronic Brachytherapy System as Incorporated in to the Physician's Current Standard of Practice
- timeFrame
- through 3 month post treatment
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Most types of endometrial (uterine) cancer Stage I and Stage II (see exclusion criteria below) * Post hysterectomy Exclusion Criteria: * Endometrial (uterine) cancer Stage IA Grade 1 * Scleroderma * Collagen vascular disease * Active Lupus
References
Publications (1)
- RESULTDickler A, Puthawala MY, Thropay JP, Bhatnagar A, Schreiber G. Prospective multi-center trial utilizing electronic brachytherapy for the treatment of endometrial cancer. Radiat Oncol. 2010 Jul 20;5:67. doi: 10.1186/1748-717X-5-67. PMID 20646289