Clinical trial · Observational
Magnetic Resonance Imaging (MRI) of Tumor Response and Cognitive Impairment in Breast Cancer Patients Undergoing Chemotherapy
Magnetic Resonance Imaging of Tumor Response and Cognitive Impairment in Breast Cancer Patients Undergoing Anthracycline-based Systemic Chemotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): No participants enrolled
Summary
Brief summary (as posted)
We will use magnetic resonance imaging (MRI) to investigate tumor changes in women with breast cancer who are receiving anthracycline-based systemic chemotherapy. We will also use MRI and cognitive tests to study the possible effects of chemotherapy on the brains of these women. The results will be compared to a control group of normal healthy women. We will try to determine if MRI can be used to predict tumor response and cognitive changes related to the chemotherapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Breast cancer, chemotherapy
- description
- Up to 15 women with breast cancer who are to undergo systemic anthracycline based chemotherapy.
- label
- Normal control
- description
- Up to 15 normal, healthy women.
Primary outcomes (0)
[]Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosed with Adenocarcinoma(ER+ve, PR+ve) * Prescribed, but not yet begun, anthracycline based systemic chemotherapy * Not prescribed Avastin * Able to read and write in English * Have signed informed consent Exclusion Criteria: * Diagnosed psychiatric disorder * Conditions that would preclude MRI (Pacemaker, metal objects in body, claustrophobia, pregnancy, etc.) * Serious, unstable medical or mental illness * Medical contraindication to any study procedure * Current alcohol or other substance use disorder (excluding nicotine) * Have not read and signed informed consent, or do not understand its contents
References
Publications (0)
Data not yet available