Clinical trial · Interventional
Comedy in Chemotherapy (COMIC) Study
NCT01037933CI-TRIAL-00002927COMICcompletedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Primary aims: To compare changes in (a) symptoms related to cancer and chemotherapy, (b) a marker of immune function (salivary immunoglobulin A), and (c) a hormonal marker of emotional stress (salivary cortisol) between two groups of patients who view a humorous or non-humorous DVD. Secondary aim: To describe the perception of patients, caregivers, and nurses regarding the overall intervention experience.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Chemotherapy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Humor intervention | Other | — | UNRESOLVED |
| Non-humor intervention (distraction) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Humor intervention
- description
- A 45-minute humorous DVD ("Bananas Bunch") using a portable DVD player.
- interventionNames
- Other: Humor intervention
- type
- ACTIVE_COMPARATOR
- label
- Non-humor intervention
- description
- A 45-minute non-humorous DVD "The A to Z of Steam Railways" using a portable DVD player.
- interventionNames
- Other: Non-humor intervention (distraction)
Primary outcomes (1)
- measure
- To compare changes in symptoms related to cancer and chemotherapy after a humor vs. non-humor intervention
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: 1. Diagnosis of cancer 2. Receiving intravenous chemotherapy in the OPO clinic at QMC 3. Has a minimum appointment time in OPO of two hours 4. Age 21 or older 5. Speaks English Exclusion Criteria: 1. Blind 2. Deaf 3. Diagnosis of head/neck cancer 4. Severe oral mucositis 5. Cognitively impaired \-
References
Publications (0)
Data not yet available
No reference posted for this study.