Clinical trial · Observational
Genetic and Environmental Risk Factors Related to Esophageal Cancer
Molecular Epidemiology of Esophageal Cancer: Pilot Project
NCT01035398CI-TRIAL-00083108active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Gathering information about genes, cigarette smoking, and diet may help doctors learn more about risk factors that may cause esophageal cancer. PURPOSE: This clinical trial is studying genetic and environmental risk factors related to esophageal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- Polymorphisms in various pathways, DNA repair, free-radical formation, inflammatory genes, metastatic potential, and cell cycle or tumor suppression in blood samples
- timeFrame
- 2000-2016
- measure
- Comparison of presence or absence of variant polymorphisms between cases and controls
- timeFrame
- 2000-2016
- measure
- Correlation between polymorphisms in blood samples and polymorphisms in tissue specimens
- timeFrame
- 2000-2016
- measure
- Analyses of dietary factors and Helicobacter pylori infection (previous vs current)
- timeFrame
- 2000-2016
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS:
* Meets 1 of the following criteria:
* Diagnosis of esophageal cancer (patient)
* Newly diagnosed disease
* Receiving care at Massachusetts General Hospital, Thoracic Oncology Center
* Friend or spouse of patient (healthy participants)
PATIENT CHARACTERISTICS:
* No concurrent psychiatric incapacity or dementia
PRIOR CONCURRENT THERAPY:
* Not specifiedReferences
Publications (0)
Data not yet available
No reference posted for this study.