Clinical trial · Interventional
Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease
Comparison of Immune Response to the Human Papillomavirus Vaccine in Young Women With and Without Inflammatory Bowel Disease
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Gardasil vaccine, a vaccine targeted towards the human papillomavirus (HPV), has been shown to prevent the transmission of several strains of HPV in young women. Women with inflammatory bowel disease (IBD) may not respond as well to this vaccine, either due to having IBD or due to immunosuppressants used to control IBD. This study will test how well women with IBD respond to the Gardasil vaccine.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Inflammatory Bowel Disease | — | UNRESOLVED | — |
| Uterine Cervical Dysplasia | Cervical Intraepithelial Neoplasia | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Human Papillomavirus Vaccine | Biological | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Human Papillomavirus Vaccine
- description
- The Gardasil HPV vaccine was administered in 3 doses: baseline, 2 months, and 6 months.
- interventionNames
- Biological: Human Papillomavirus Vaccine
Primary outcomes (1)
- measure
- Twelve Month Antibody Response to the Human Papillomavirus (HPV) Vaccine (Geometric Mean Titers [GMT])
- timeFrame
- One year
- description
- Anti-HPV levels were determined by an assay conducted by Merck \& Co, Inc. and expressed as milliMerck units per milliliter (mMU/mL).
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 9 Years
- Maximum age
- 26 Years
Show eligibility criteria text
Inclusion Criteria: 1. Women 9-26 years of age 2. Have inflammatory bowel disease (ie. Crohns disease or ulcerative colitis) Exclusion Criteria: 1. Pregnancy 2. Taking corticosteroids 3. Allergy to yeast aluminum component of the HPV vaccine 4. Positive for all HPV types in the Gardasil vaccine-6, 11, 16, 18
References
Publications (0)
Data not yet available