Clinical trial · Interventional
Low-energy Laser Therapy for Prevention of Oral Mucositis in Children
Evaluation of Low-energy Laser Therapy for Prevention and Reduction of Severity of Oral Mucositis in Children "Mucositis Laser 1"
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Oral mucositis represents a major complication of cytotoxic chemotherapy among cancer in children. Low-power laser therapy (LPLT) has been used to reduce the incidence of oral mucositis in patients who are receiving high-dose chemotherapy. The aim of this study is to compare two preventives energies delivered of LPLT to oral mucosa in decreasing the severity of mucositis in children.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Oral Mucositis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LLLT :low level laser therapy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Mucositis scale - World Health Organization (WHO)
- timeFrame
- after delivering a dose of 2 J/cm2/d
Secondary outcomes (8)
- measure
- Mucositis period
- timeFrame
- after delivering a dose of 8 J/cm2/d
- measure
- Mucositis free survival
- timeFrame
- after delivering a dose of 8 J/cm2/d
- measure
- Pain intensity
- timeFrame
- after delivering a dose of 8 J/cm2/d
- measure
- Morphinic administration
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 0 at 18 years * patients receiving therapy with agents likely to cause severe mucositis (grade 3 or 4) * Patients who had developed severe mucositis previously in any chemotherapy, and receiving the same. * Healthy oral mucosa * informed consent Exclusion Criteria: * \- Infection active and proved, viral, bacterial or fungal oral cavity * Malignant pathology in the oral cavity * Preliminary local irradiation of the oral cavity * Simultaneous treatment by an agent of prevention or treatment of mucositis in investigation * Inclusion in a protocol with oral mucositis as one of the assessment criteria * Absence of consent lit by parents or child
References
Publications (0)
Data not yet available