Clinical trial · Observational
Wound Healing In Diabetes (WHy) Study
Molecular and Genetic Analysis of Disturbed Wound Healing in Barbadians With Diabetic Foot Ulcers
NCT01002521CI-TRIAL-00002732WHyunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational study aims to identify risk factors and molecular mechanisms of impaired wound healing, to guide better foot care in the diabetic population.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Diabetes Mellitus | — | UNRESOLVED | — |
| Impaired Wound Healing | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Cases
- description
- Persons With Diabetes (PWD) who have current non-healing ulcer(s)
- label
- Controls
- description
- Persons With Diabetes (PWD) with no current ulcers and no history of ulcers
Primary outcomes (1)
- measure
- Genetic Phenotyping (Haptoglobin and TRAPS)
- timeFrame
- 18 months
Secondary outcomes (3)
- measure
- Reactive Hyperemia Index and Augmentation Index
- timeFrame
- 18 months
- measure
- Depression
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * clinical diagnosis of diabetes * Barbadian national * self reported ethnicity of Black/African descent * clear knowledge of ulcer history Exclusion Criteria: * no clinical diagnosis of diabetes * non-national of Barbados * self reported ethnicity not Black/African Descent * unclear knowledge of ulcer history
References
Publications (2)
- BACKGROUNDHennis AJ, Fraser HS, Jonnalagadda R, Fuller J, Chaturvedi N. Explanations for the high risk of diabetes-related amputation in a Caribbean population of black african descent and potential for prevention. Diabetes Care. 2004 Nov;27(11):2636-41. doi: 10.2337/diacare.27.11.2636. PMID 15504998
- BACKGROUNDHambleton IR, Jonnalagadda R, Davis CR, Fraser HS, Chaturvedi N, Hennis AJ. All-cause mortality after diabetes-related amputation in Barbados: a prospective case-control study. Diabetes Care. 2009 Feb;32(2):306-7. doi: 10.2337/dc08-1504. Epub 2008 Nov 4. PMID 18984775