Clinical trial · Interventional
Indole-3-Carbinol Effects on Estrogen Metabolism
Effects of Dietary Indole-3-Carbinol on Estrogen Metabolites Across a Wide Range of Body Mass Index: Implications for the Prevention of Endometrial Cancer in Obese Women
NCT00988845CI-TRIAL-00042255terminatedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Slow accrual in the high BMI group
Summary
Brief summary (as posted)
This study will test a dietary supplement, indole-3-carbinol, for improving the estrogen profile in women across a range of body mass index.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Obesity | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Indole-3-carbinol | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Indole-3-carbinol
- interventionNames
- Dietary Supplement: Indole-3-carbinol
Primary outcomes (1)
- measure
- Change in urinary 2/16-hydroxyestrone ratio
- timeFrame
- 8 weeks
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 30 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * woman aged from 30 - 50 years * regular menstrual cycle Exclusion Criteria: * taking hormone replacement or hormonal contraception * thyroid disorder * uncontrolled asthma * BMI under 18.5 * allergy to cruciferous vegetables
References
Publications (0)
Data not yet available
No reference posted for this study.