Clinical trial · Interventional
Acupressure Wristbands or Standard Care in Controlling Nausea Caused by Chemotherapy
The Effectiveness and Cost Effectiveness of Acupressure for the Control and Management of Chemotherapy-related Nausea.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Acupressure wristbands may prevent or reduce nausea caused by chemotherapy. It is not yet known whether acupressure wristbands are more effective than standard care in controlling acute and delayed nausea. PURPOSE: This randomized phase III trial is studying acupressure wristbands to see how well they work compared with standard care in controlling nausea caused by chemotherapy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety Disorder | — | UNRESOLVED | — |
| Nausea and Vomiting | — | UNRESOLVED | — |
| Unspecified Adult Solid Tumor, Protocol Specific | Adult Solid Neoplasm | ALIAS | 0.85 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| acupressure therapy | Procedure | — | UNRESOLVED |
| medical chart review | Other | — | UNRESOLVED |
| quality-of-life assessment | Procedure | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
| sham intervention | Procedure | — | UNRESOLVED |
| standard follow-up care | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Incidence and severity of nausea as assessed by the Rhodes Index of Nausea & Vomiting before and after chemotherapy
Secondary outcomes (6)
- measure
- Incidence and extent of acute and delayed nausea and vomiting by the MASCC Antiemesis Tool at day 10 of each course
- measure
- Quality of life as assessed by FACT-G at baseline and at day 10 of each course
- measure
- Anxiety as assessed by the Hospital Anxiety & Depression Scale at baseline
- measure
- Expectation for nausea and vomiting as assessed by the Patient Expectations of Nausea/Vomiting after each chemotherapy course
- measure
- Measure of blindness (to intervention vs sham) assessed after chemotherapy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Diagnosis of any cancer * Scheduled to receive their first chemotherapy course * Scheduled to receive highly, moderately, or low-emetogenic chemotherapy * Scheduled to receive a chemotherapy regimen given as a single administration at the beginning of the course repeated in 3-week courses * Currently receiving adjuvant chemotherapy as outpatient * Acupressure wristband-naïve (in terms of never having tried such a wristband; may have seen or heard about such wristbands) PATIENT CHARACTERISTICS: * Able to perform self care (i.e., no inability to use wristbands appropriately or mental incapacity preventing continuous and optimal use of wristbands) as judged by the investigators * No liver disease * No metabolic risk factors for nausea (i.e., electrolyte imbalances causing nausea/vomiting) * No mechanical risk factors for nausea (i.e., intestinal obstruction) * No nausea and/or vomiting due to use of opioids * No lymphedematous arms * No chronic alcohol use PRIOR CONCURRENT THERAPY: * No concurrent radiotherapy * No concurrent chemotherapy regimens as inpatients
References
Publications (0)
Data not yet available