Clinical trial · Interventional
Comparison of Neuro-navigational Systems for Resection-Control of Brain Tumors
Comparison of Two Neuro-navigational Systems for Resection-control of Intra-axial Brain Tumors. The PoleStarN-20 Intra-operative Magnet Resonance Imager and the Mison SonoWand Intra-operative Ultrasound System
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Purpose: * Improvement of extent of resection by the use of intraoperatively acquired image data sets to navigate. * Better define the role of different intra-operative imaging modalities, used to update the navigational data set, in aiding the surgeon during resection of intra-axial brain lesions. * To examine the cost-effectiveness of different intraoperative navigational systems as a function of operative time and Operative time (Surgery including imaging) There is increasing neuro-oncological evidence that extent of resection might have an impact in particular in low-grade lesions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Glioma | Glioma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intraoperative MR (PoleStar N-20, Medtronics) | Device | — | UNRESOLVED |
| Intraoperative Ultrasound (Sonowand, Mison) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Intraoperative MR
- description
- Use of intraoperative MR during resection of intraaxial tumor, Glioma
- interventionNames
- Device: Intraoperative MR (PoleStar N-20, Medtronics)
- type
- OTHER
- label
- Intraoperative Ultrasound
- description
- Use of intraoperative ultrasound during resection of intraaxial tumor, Glioma
- interventionNames
- Device: Intraoperative Ultrasound (Sonowand, Mison)
Primary outcomes (1)
- measure
- The primary end point of the study is assessment and comparison of intra-operative Magnet Resonance Imaging and ultrasound to better define its impact on the extent of resection.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients must have neuro-radiological evidence of a brain lesion. Eligible are all histological types of brain lesions. * \> 18 years of age. * Male and female. * Patient must be a surgical candidate, according to general anesthetic and neurosurgical criteria. * Patient should be able to undergo MRI. * Informed consent as per protocol. Exclusion Criteria: * Patient unwilling to undergo surgery for resection of brain tumor. * Patient medically not eligible to undergo craniotomy. (Medical contraindication). * Patient has a medical contraindication or is unwilling to undergo MRI scanning (pacemaker, other metal device ot parts in head or body,). * Kidney function compromise (Creatinine values \> 1.4 mg/dL).
References
Publications (0)
Data not yet available