Clinical trial · Interventional
Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer
A Prospective Multicenter Study Comparing Endobronchial and Endoscopic Ultrasound-Guided FNA to Mediastinoscopy/Thoracoscopy in the Staging and Early Detection of Metastases in Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Similar study published results
Summary
Brief summary (as posted)
This is a prospective randomized clinical trial with the study cohort comprised of all male and female patients over the age of 21 presenting to the study site for evaluation of lung cancer. The study will enroll 300 subjects, with 150 in each arm. Three sites will be in the study, Mayo Rochester, Mayo Jacksonville and Medical University of South Carolina. Mayo Rochester will enroll approximately 125 subjects. This study does not require subjects to undergo any additional procedures than what they would receive per standard medical care. The consenting subjects will receive EUS and /or EBUS- guided FNA or Mediastinoscopy/Thoracoscopy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non Small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EBUS/EUS | Procedure | — | UNRESOLVED |
| Mediastinoscopy/thoracoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- traditional mediastinoscopy/thoracoscopy
- description
- Traditional Mediastinoscopy used to detect or stage lung cancers.
- interventionNames
- Procedure: Mediastinoscopy/thoracoscopy
- type
- ACTIVE_COMPARATOR
- label
- EBUS/EUS
- description
- Minimal invasive technique for staging/detecting lung cancer.
- interventionNames
- Procedure: EBUS/EUS
Primary outcomes (1)
- measure
- Develop an integrated staging technique to detect early metastases in lung cancer which should affect patient outcomes more accurately than conventional staging techniques.
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Age 21 years or greater * Pt is a surgical candidate for mediastinoscopy, thoracoscopy, or lung resection * Known or suspected non-small cell carcinoma of the lung eligible for resection * CT scan performed within 45 days prior to evaluation for study participation * PET scan performed within 45 days prior to evaluation for study participation Exclusion Criteria: * Pathologically proven metastatic disease * History of malignancy within 5 years other than (skin) basal cell carcinoma * Enlarged ipsilateral mediastinal lymph nodes \> 2.5 cm in diameter * Peripheral T1 tumors with normal mediastinal lymph nodes on CT and PET
References
Publications (0)
Data not yet available