Clinical trial · Interventional
Hot and Cold Biopsy Forceps in the Diagnosis of Endobronchial Lesions
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A new electrocautery bronchoscopy biopsy forceps is now commercially available and may prevent bleeding following biopsy. Only one study used this device wherein the authors concluded that the use of hot biopsy forceps for endobronchial biopsy does not appear to have a negative impact on the pathological samples, and that there was a statistically significant, albeit clinically insignificant reduction in bleeding score with hot biopsy forceps. Therefore, a randomized controlled study is required in which the hot and cold biopsies are performed to evaluate the tissue effect of the hot biopsy forceps on histopathological diagnosis.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endobronchial Growth | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cold biopsy forceps | Device | — | UNRESOLVED |
| Hot biopsy forceps | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Hot biopsy
- description
- Hot biopsy i.e. Endobronchial biopsies taken with the application of an electrocoagulation current by an electrocoagulation-capable biopsy forceps
- interventionNames
- Device: Hot biopsy forceps
- type
- ACTIVE_COMPARATOR
- label
- Cold biopsy
- description
- Cold biopsy i.e. Endobronchial biopsies taken without the application of an electrocoagulation current by an electrocoagulation-capable biopsy forceps
- interventionNames
- Device: Cold biopsy forceps
Primary outcomes (1)
- measure
- Quality of pathological specimen
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. All patients undergoing routine bronchoscopic biopsy for various indications 2. More than 18 years of age Exclusion Criteria: 1. Bleeding diathesis 2. On pacemaker or implanted defibrillator 3. On anticoagulation therapy 4. Poor cardiopulmonary reserve 5. Marked hypoxemia 6. Uncooperative patient 7. Enrollment in the previous study
References
Publications (0)
Data not yet available