Clinical trial · Observational
Evaluation of Preoperative Endobronchial Ultrasound (EBUS) in Non Small Cell Lung Cancer (NSCLC)
Medico-economic Evaluation of a Preoperative Algorithm Including EBUS for NSCLC Initial Staging
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to assess both the role and cost-effectiveness of EBUS in preoperative Non small cell lung cancer staging. This controlled multicentric study will be conducted in 22 centers in France. The study design includes two prospective phases. In phase 1, one investigator in each center will prospectively be evaluated for its ability to perform EBUS, with a required goal of 9 informative samplings out of 10 consecutive patients. The phase 2 will include the medico-economic assessment of the technique in the preoperative setting. A maximum of 420 patients for each phase is forecasted.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non Small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EBUS | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- NON SMALL CELL LUNG CANCER
- description
- Non small cell lung cancer, with clinical N2 disease, otherwise operable.
- interventionNames
- Procedure: EBUS
Primary outcomes (1)
- measure
- number of mediastinoscopy avoided
- timeFrame
- 24h
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * adult patients over 18 * non small cell lung cancer histologically or cytologically proved * Clinical Stage IIIA * anatomically and functionally resectable Exclusion Criteria: * uncorrected bleeding disorders * absence of lymphadenopathy superior to 1cm in small axis at CT scan * contraindication to bronchoscopy * extrathoracic or intrathoracic metastasis * respiratory function tests not compatible with curative resection of lung cancer
References
Publications (1)
- DERIVEDChouaid C, Salaun M, Gounant V, Febvre M, Vergnon JM, Jouniaux V, Fournier C, Lachkar S, Hermant C, Raspaud C, Quantin X, Quiot JJ, Molard A, Dayen C, Marquette CH, Lena H, Zalcman G, Thiberville L. Clinical efficacy and cost-effectiveness of endobronchial ultrasound-guided transbronchial needle aspiration for preoperative staging of non-small-cell lung cancer: Results of a French prospective multicenter trial (EVIEPEB). PLoS One. 2019 Jan 7;14(1):e0208992. doi: 10.1371/journal.pone.0208992. eCollection 2019. PMID 30615623