Clinical trial · Observational
Study of Blood and Tumor Samples From Men With an Inherited Risk of Prostate Cancer
UK Genetic Prostate Cancer Study
NCT00959023CI-TRIAL-00011900unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Studying samples of blood and tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify genes related to cancer. PURPOSE: This clinical trial is studying blood and tumor samples from men with an inherited risk of prostate cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| medical chart review | Other | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Prostate cancer (PC) predisposition (PCP) genes
Secondary outcomes (7)
- measure
- Association of PCP genes with disease and treatment parameters
- measure
- Association of PCP with environmental factors
- measure
- Family history of PC
- measure
- Relative risk of developing PC
- measure
- Increased risk relatives of PC patients are to develop cancers other than PC
- measure
- Markers of PC that are associated with PCP genes
Eligibility
Eligibility (as posted)
- Sex
- Male
Show eligibility criteria text
DISEASE CHARACTERISTICS:
* Meets 1 of the following criteria:
* Diagnosis of prostate cancer meeting any of the following criteria:
* Attending prostate clinics at The Royal Marsden NHS Foundation Trust
* Any age at diagnosis
* Not attending prostate clinics at The Royal Marsden NHS Foundation Trust, meeting 1 of the following criteria:
* No older than 60 years at diagnosis
* Diagnosis in two relatives where one is ≤ 65 years at diagnosis
* At any age in a cluster with 3 or more cases
* Any unaffected male relatives of men who are already taking part in the study
PATIENT CHARACTERISTICS:
* Able to understand the information sheet and give informed consent
* No man who is too ill to take part
PRIOR CONCURRENT THERAPY:
* Not specifiedReferences
Publications (0)
Data not yet available
No reference posted for this study.