Clinical trial · Observational
Observational Study for the Cytofluorimetric Analysis of Cerebrospinal Fluid in Non-Hodgkin's Lymphoma Patients
Observational Retrospective Multicenter Study for the Citofluorimetric Analysis of Cerebrospinal Fluid Vs Conventional Method in Patients With Aggressive Non-Hodgkin's Lymphoma Without Leptomeningeal Disease
NCT00949741CI-TRIAL-00012425CFMcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to define if flow cytometry has more sensitivity for detecting neoplastic cells in cerebrospinal fluid versus conventional cytology.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Burkitt's Lymphoma | Burkitt Lymphoma | ALIAS | 0.90 |
| Diffuse Large Cell Lymphoma | — | UNRESOLVED | — |
| Lymphoblastic Lymphoma | Lymphoblastic Lymphoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Evaluation of diagnostic agreement of citofluorimentria flow in the research of lymphoma cells in the cerebrospinal fluid vs cell morphology.
- timeFrame
- Evaluation at diagnosis
- description
- Evaluation of diagnostic agreement of citofluorimentria flow in the research of lymphoma cells in the cerebrospinal fluid vs cell morphology. The second test will be performed independently and without the cytologist is aware of the outcome of the analysis by flow cytometry.
Secondary outcomes (1)
- measure
- Collection of all paper forms
- timeFrame
- 1 year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Diagnosis of * Diffuse large cell lymphoma HIV positive, * Lymphoblastic lymphoma, * Burkitt's lymphoma, * Mantle cell lymphoma blastoid type. 2. DLCL patients who presented one risk factor for leptomeningeal involvement as: * testis, bone marrow, orbit, palate, paranasal cavity or peridural disease localization, * 2-3 age-adjusted IPI score with more than 1 extranodal site and LDH \> normal. 3. Patients with cytologic and flow cytometry on cerebrospinal fluid at diagnosis. Exclusion Criteria: 1\. Patients with clinical or strumental evidence of meningeal localization disease.
References
Publications (0)
Data not yet available
No reference posted for this study.